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Eggs Choline And Prostate Cancer

Love Eating Eggs Then Read This To Know If It Is Really Healthy For You Especially If You Are Over 40 Years Old

Eggs, Choline, and Cancer

Written by Debjani Arora | Updated : December 13, 2017 5:49 PM IST

Man, if you love to eat eggs and cannot imagine having your breakfast without including this nutrient-rich food on your plate, then this headline might be a little upsetting for you. But let us remind you that any food had in excess can lead to troubles even the nutritious eggs which have many health benefits. For men, with age, the risk of prostate cancer increases, a reason why they are advised to go for a PSA test annually post 40 or 50 to keep a tab on the same. An early detection would help in treating the same with positive outcomes.

However, apart from age, diet practices also influence the risk of prostate cancer. Sometimes even nutrition dense foods can be a culprit and make you sick in one way or the other. Today we are trying to explore the relationship between eggs and prostate cancer.

Are eggs bad for your prostate?

Putting Eggs Into Context

When it comes to eggs, how the eggs are consumed and how the eggs are sourced are both important factors, and so these are things to consider when looking at studies concerning eggs and when thinking about our egg intake.

Chicken eggs are high in cholesterol and are actually one of the foods with the highest levels of cholesterol that we eat. But eaten by themselves or alongside healthy whole foods, the effect of egg consumption on blood cholesterol is actually minimal, particularly when compared with the effect of trans fats and saturated fats.

In fact, when we look more closely at the overall context of the participants diets in studies examining egg consumption, we realize that it may well be the foods traditionally eaten alongside eggs that are increasing the risk of chronic illnesses: foods such as bacon, sausage, butter, cheese, and refined carbohydrates like white bread and sugar. Eggs are also a hidden ingredient in numerous baked goods. In many people with diets high in eggs, the eggs are often one part of an overall unhealthy dietary pattern that contributes to risk factors for disease.

For example, processed foods like those listed above are unequivocally bad for us, and there are hundreds of studies linking them to increased diabetes, cardiovascular disease, and cancer risk: particularly processed meats like bacon, hotdogs, and deli meats, which are actually classified as carcinogens.

Reducing Prostate Cancer Risk Through Diet

If you are concerned about developing cancer, then you can follow the existing dietary and lifestyle guidelines for reducing prostate cancer risk, which includes:

  • Limiting processed foods in your diet. The majority of processed foods contain additives, sugar, and salt. These chemical additives are not food-based, and many of them are anti-microbial, which means they not only limit the growth of bacteria and other microbes, to keep the food from rotting, but they also affect the microbes that keep our gut healthy.
  • Reducing red meat consumption. High intakes of red meat have been associated with an increased risk of prostate cancer. It was previously reported in the Health Professionals Follow-up Study that red meat intake was associated with an increased risk of metastatic prostate cancer based on follow-up from 1986 to 1996.
  • Avoiding cows milk and other high-fat dairy products. Research has shown that men who consume a lot of dairy products have an increased likelihood of developing prostate cancer than men who dont eat calcium-heavy diets.
  • Increasing the amount of fruits and vegetables in your diet, which are rich in antioxidants, vitamins, and minerals. In fact, recent research suggests that a vitamin-rich plant-based diet may lower the risk of prostate cancer. Try including cruciferous vegetables, such as broccoli, cabbage, and kale, which are rich in beta carotene.

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The Role Of Choline In Phospholipid Metabolism

Choline is utilized for the de novo synthesis of PtdCho via the Kennedy pathway . The Kennedy pathway involves three reactions. In the first step, choline kinase catalyzes the phosphorylation of choline into PCho. This reaction can be a rate-limiting step for PtdCho biosynthesis . CHK has three isoforms all of them have choline kinase activity . The second reaction in the Kennedy pathway is catalyzed by the

Eggs Increase The Risk Of Lethal Prostate Cancer

The Truth on Eggs, Choline &  Prostate Cancer

Researchers at Harvard studied the connection between egg consumption and lethal prostate cancer. The findings are published in an article entitled, Choline Intake and the Risk of Lethal Prostate Cancer: Incidence and Survival. The study showed that those consuming the highest amount of choline had a 70% increased risk of lethal prostate cancer.

Another study showed that a group of men who ate 2.5 eggs per week had an 81% increased risk of lethal prostate cancer compare to the men who ate fewer than 0.5 eggs per week.

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Do Eggs Cause Prostate Cancer

Eating eggs could increase your chances of being diagnosed with lethal prostate cancer, a new study in the journal Cancer Prevention Research reports. But before you swear off your morning scramble, understand what the research actually showsand what it doesnt.

The study followed 27,607 men from 1994 to 2008. Guys who consumed 2.5 or more eggs per week had an 81 percent increased risk for cancer that spread to the organs or caused death compared to men who consumed less than half an egg per week before their diagnosis.

We dont fully understand what it is about eggs that may increase risk of lethal prostate cancer, says study author Erin Richman, Ph.D.

At MH, weve long touted eggs as a protein-packed, healthy breakfast option. Theyre even one of our 40 Foods with Superpowers. So what could be behind this? Here are a few possible explanations.

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Eating eggs could be a sign of an unhealthy lifestyle?The men in the study who consumed more eggs had a higher average BMI, exercised less vigorously, and were more likely to be smokers, have a history of type-2 diabetes, and have a family history of prostate cancer. In other words, they were more likely to have risk factors besides their morning eggs.

A component of eggs helps prostate cancer cells grow?The egg is a super food when it comes to our bodies ability to use its proteins and other nutrients.

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In a Harvard study, investigators evaluated the diets of 1,294 men who had early stage prostate cancer. The two-year study included men who had participated in the Cancer of the Prostate Strategic Urologic Research Endeavor. The authors discovered that while red meat, fish, total poultry, and skinless poultry were not associated with the recurrence or progression of prostate cancer, egg intake was. When compared with men who rarely ate eggs at all, those who consumed eggs daily had a twofold increase in the risk of prostate cancer progression.

The reason for this increased risk was postulated to be the choline in eggs, which is present in significant amounts . In fact, eggs are the richest source of choline. Previous research has shown that this water-soluble, vitamin-like nutrient has been associated with a higher risk of developing prostate cancer. Therefore, it could be extrapolated that the choline in eggs may increase the chances of both getting the disease and spreading it.

But the dangers of consuming eggs if you have prostate cancer doesnt end there. Other research has shown that choline also significantly increases the risk of dying of prostate cancer a 70% increased risk of lethal prostate cancer to be exact. Another study quoted an even higher percentage: 81 percent higher risk of deadly prostate cancer among men who ate 2.5 or more eggs weekly.

ReferencesGregor M. Eggs, choline and cancer. 2013 October 14

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While Our Conclusion Was Tempered By The Potential For Publication Bias And Confounding High Egg Intake May Be Associated With A Modestly Elevated Risk Of Breast Cancer And A Positive Association Between Egg Intake And Ovarian And Fatal Prostate Cancers Cannot Be Ruled Out

Eggs and prostate cancer. The only thing worse was poultry with skin consumption which showed up to 4 times the risk of progression among high-risk men. Apparently choline from eggs and carnitine from red meat are structurally similar and both metabolize into TMAO. Greater intake of choline found in meat dairy and eggs which has been found to increase prostate cancer risk.

Lets take a look at the scientific data. As you can see at 417 in my video though there may be more evidence for elevated breast cancer risk with egg consumption than prostate cancer risk the only other study to date on TMAO and cancer looked at prostate cancer and did indeed find a higher risk. Reduce the amount of dairy products you eat each day.

It should be noted however that men with high egg consumption also had higher red meat intake Keum 2015. My 4 week post surgery PSA 041 and 6. Thats a doozy since eggs are a staple diet for most and a preferred source of protein for many.

Egg yolks have more of an affinity of causing prostate cancer while red meat causes colorectal cancer. Men who consumed 25 or more eggs per week had an 81 increased risk of lethal prostate cancer compared to men who consumed less than 05 eggs per week HR. But study results have been mixed and the risk associated with dairy products is thought to.

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The Incredibly Inedible Egg

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What Do Researchers Believe Is The Reason For Increased Cancer Risk

C11 Choline PET Scan by Dr Eugene Kwon

It has been found that a large amount of cholesterol is required for malignant cells to support their rapid growth . Meaning, cancer cells can use cholesterol to fuel its growth.

As mentioned previously, foods that contain high amounts of cholesterol likely contain high amounts of saturated fat, but also choline and protein all of which are believed to play a role in the development and/or growth of cancer cells.

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Digesting The Latest Research On Eggs

Eggs are back in the news again. A study from the March 2019 JAMA found that higher intakes of cholesterol and eggs were associated with a greater risk of cardiovascular disease and death.

The researchers reported that ingesting an additional 300 milligrams of cholesterol per day raised this risk, as did eating an average of three to four eggs per week.

Should we finally resign ourselves to taking our toast without a sunny-side-up yolk? Not so fast.

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The reason for this increased risk was postulated to be the choline in eggs, which is present in significant amounts . In fact, eggs are the richest source of choline. Previous research has shown that this water-soluble, vitamin-like nutrient has been associated with a higher risk of developing prostate cancer. Therefore, it could be extrapolated that the choline in eggs may increase the chances of both getting the disease and spreading it.

But the dangers of consuming eggs if you have prostate cancer doesnt end there. Other research has shown that choline also significantly increases the risk of dying of prostate cancer a 70% increased risk of lethal prostate cancer to be exact. Another study quoted an even higher percentage: 81 percent higher risk of deadly prostate cancer among men who ate 2.5 or more eggs weekly.

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Surgical procedures to remove the diseased prostate are usually necessary. Surgical procedures are not always necessary. If the disease is caused by bacterial infections, a doctor can treat the symptoms using alpha-blockers or surgery. Physical therapy, relaxation exercises, and warm baths are all recommended. A physician may also prescribe antibiotics to cure the infection. A bacterial infection can also cause a recurrence of the condition.

An enlarged prostate can be uncomfortable for both men and women. Some of the symptoms of an enlarged male reproductive organ include a weakened urine stream, urgent need to urinate, and urinary tract infections. BPH can also cause damage to the kidneys. A sudden inability to urinate can be life-threatening, as it can lead to bladder and kidney damage. Unfortunately, most men with enlarged prostrates put up with the symptoms for years before they seek treatment. However, many of the men with symptoms finally decide to go to a doctor for proper gynecological evaluation and to begin enlarged prostatic therapy.

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Eggs, cancer, and motivated reasoning

Symptomatic treatment of an enlarged prostate usually involves a combination of medication and lifestyle changes. A diet rich in fruits and vegetables may be the best option if you suffer from chronic urination. It will help the body adjust to the increased size of the prostate. Also, taking regular urination intervals will help retrain the bladder to function properly. Inactivity also contributes to urine retention, and cold temperatures can increase the urge to urinate.

Invasive treatment of enlarged prostate includes medication that relieves the pressure on the urethra and bladder. However, if the condition is severe, it may require surgical intervention. If treatment is not successful, the enlarged prostate can become a potentially life-threatening disease. As the hormone levels in the body change, the enlarged prostate can lead to various complications, including urinary retention and even cancer. This is why it is critical to see a doctor for further evaluation.

A physician can recommend a number of treatments to address an enlarged prostate. An enlarged prostate will require surgery to relieve the symptoms. In most cases, surgical treatment for an enlargement of the penis is enough. Moreover, a doctor may recommend a course of treatment based on symptoms. A TURP procedure is not painful and requires less recovery time than open surgery. The recovery period will be shorter and less traumatic.

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Why Are Eggs Connected To An Increase Risk Of Prostate Cancer

It seems like the connection between eggs, and prostate cancer is on an nutrient called choline. The crux is that choline is essential for human life and mental performance and we would not do well without it.

And thats what makes the association with nutrition and cancer confusing and frustrating.

Heres another thing, choline is used as a tracer for a specific type of PET scan called Choline C-11 PET scan to find smaller prostate cancer cells in the body that cant be found with other imaging technology.

What does this mean?

A tracer is a substance introduced into the body gobbled up by cancer cells so such cells can light up in images and location of cancer can be found.

Amongst integrative oncologists, it is often said that sugar is bad for cancer because glucose is taken up by cancer cells in another type of PET scan called F-FDG PET.

If the argument with excess sugar consumption is true, then it must apply to choline as well. No?

Lets Take A Look At The Scientific Data Regarding Egg Consumption And Prostate Cancer

In The Health Professionals Follow-Up Study , a study observing over fifty thousand male health professionals since 1986 noticed that men who consumed 2.5 eggs per week had a 1.8-fold increased risk of developing lethal prostate cancer compared with men who consumed < 0.5 eggs per week. However, this study found no association between consumption of eggs and risk of deadly prostate cancer after diagnosis.

On the other hand, results from 15 prospective cohort study involving 842,149 men from North America, Europe, Australia, and Asia, examined the association of incidence of prostate cancer and the intake of unprocessed and processed red meat, seafood, eggs, and poultry. No association among unprocessed red meat, processed red meat poultry and seafood and prostate cancer was made.

However, a connection was detected between eggs intake and fatal prostate cancers risk.

The Cancer of the Prostate Strategic Urologic Research Endeavor , another very large male study found an increased risk of recurrence for higher intakes of eggs around the time of diagnosis.

Egg intake in CaPSURE was higher, with a mean of 7.9 servings per week compared to 3.2 servings per week in our population. Also, CaPSURE, men who consumed the most eggs after prostate cancer diagnosis had a two-fold increased risk of prostate cancer recurrence compared with men who consumed the least eggs

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An enlarged prostate can also be the cause of other problems. If the enlarged prostate is causing symptoms, the best treatment would be a natural remedy. In the meantime, there are treatments for a wide range of conditions that cause a man to experience pain. A common surgical procedure involves an electric loop, laser, or electro-stimulation. The procedure is a safe and effective option for treating enlarged or symptomatic BPH.

/5the Link Between Diet And Cancer

Carnitine, Choline, Cancer and Cholesterol: The TMAO Connection

Various studies have been done backing the role of dietary choline in cancer prevention. It is believed that not getting enough of it is linked to an increased risk of fatal health issues. On the other hand, it was also proven that too much intake of the same nutrient can increase the risk of lethal prostate cancer by 70 per cent. Studies have found that choline is found in concentration in prostate cancer cells, blood concentration that can further increase the risk of cancer.

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