Formulation Of Croton Membranaceus
Various formulations of the root extract is available ethanol extracts and aqueous extracts . Bayor et al. demonstrated that the oral capsule was the most appropriate dosage form for C. membranaceus. In their study, they formulated both liquid and solid oral dosage forms from the ethanol extract of C. membranaceus root and investigated their physicochemical properties, release effects and suitability in comparison with aqueous decoctions and unformulated powdered plant material.
They observed that the ethanol extract had characteristics similar to the aqueous decoction, but unlike the later, it maintained its specifications and stability throughout the period of study. The use of large volumes, convenience and short shelf life, was said to limit the application of aqueous decoctions. The assessed properties of the prepared tablets and capsules met all the specifications required for good quality and had the advantage that it could be used in simple and convenient doses of one tablet or capsule, three times a day, in place of unstable decoctions and large volume solutions.
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Medicine For Prostate Cancer In Ghana
Naturopathy or naturopathic medicine is a form of alternative medicine employing a wide array of natural treatments, including homeopathy, herbalism, and acupuncture, as well as diet and lifestyle counseling. Naturopaths favor a holistic approach with non-invasive treatment and generally avoid the use of surgery and drugs. Naturopathic philosophy is based on a belief in vitalism and self-healing, and practitioners prefer methods of treatment that are not compatible with evidence-based medicine.
Naturopathic practitioners can be divided into three categories: traditional naturopaths naturopathic physicians and other health care providers that provide naturopathic services. Naturopathic physicians employ the principles of naturopathy within the context of conventional medical practices.
Naturopathic medicine is an approach to health care that uses natural, non-toxic therapies to treat the whole person and encourage the self-healing process. Naturopathic clinicians treat a variety of conditions, including digestive issues, respiratory conditions, chronic fatigue syndrome and cancer.
As part of the intake process, youll meet with your registered naturopathic oncology practitioner, who will review your history and make recommendations from a wide variety of natural therapies. Our naturopathic oncology provider also will review current supplements to identify herb-drug-nutrient interactions.
Herbal and botanical preparations, including herbal extracts and teas.
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Animal Studies On Croton Membranaceus
Various animal studies have been performed on C. membranaceus. In a study by Afriyie et al on the treatment of BPH with C. membranaceus in an experimental animal model, they set out to evaluate if C. membranaceus root extract could attenuate the development of BPH in adult male Sprague-Dawley rats. Though they did not find statistical difference in prostate size in those receiving C. membranaceus root extract, there was attenuation of the growth of the stromal and epithelium cells. This finding was similar to the use of finasteride in a comparable group with an associated shrinkage of the prostate. Noteworthy was lowering of the prostate specific antigen in the group.
As noted, an earlier study that sort to determine if C. membranaceus led to reduction in dihydrotestosterone levels in rat serum, found it to inhibit the synthesis of dihydrotestosterone by prostatic 5-reductase in the rat in vitro, but did not confirm that C. membranaceus had significant effect in lowering dihydrotestosterone levels in vivo.
Another study evaluated Mitochondria-dependent apoptogenic activity of aqueous root extract of C. membranaceus against human BPH-1 cells and found that C. membranaceus root extract induced a significant dose-dependent inhibition in the proliferation of BPH-1 cells with significant DNA fragmentation, and the induction of mitochondria- dependent apoptosis of the BPH-1 cell lines.
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Top Ten Herbs For Prostate Health
If you have a frequent need to urinate, need to get up to go to the bathroom at night, leak urine or can’t seem to empty your bladder, or even notice blood in your urine, it is time to see a doctor. Some natural remedies can also promote prostate health, however, and here we will take a look at them.
7. Xue lian hua
8. Ryegrass pollen extract is made from three different kinds of grass pollen, namely rye, timothy, and corn. Research demonstrates that Cernilton improves the urological symptoms of men suffering from benign prostatic hyperplasia, and nocturnal urination in particular.
9. Stinging nettle provides an abundance of nutritional benefits, offering iron, magnesium, calcium, vitamin A, vitamin B6, and plenty of dietary fiber. It is used as an alternative remedy for numerous different conditions including arthritis, hay fever, and to induce lactation. Stinging nettle extract is also useful for prostate health, for which it is often recommended in combination with other treatments such as saw palmetto. Research revealed that nettles have the ability to fight prostate cancer cells.
10. Beta-sitosterol, a plant sterol, is commonly found in vegetable oils and nuts as well as avocado. Its anti-cancer potential and the premise that it can hold off the urological symptoms of benign prostatic hyperplasia makes it a promising choice for any man who wishes to preserve his prostate health.
Your Underlying Medical Issue
The clinical diagnosis for an enlarged prostate gland is benign prostatic hyperplasia , and its the most common cause of frequent urination or urinary pain in men.
But these symptoms dont always mean that your prostate is enlarged. It could be inflamed or infecteda condition known as prostatitis that requires antibiotics. Your urinary troubles could also be a side effect from another medication.
Taking an over-the-counter supplement without having a doctor find and address the true source of your symptoms is dangerous, even if it provides temporary relief.
Recommended Reading: Prostate Artery Embolization Side Effects
More Herbal Cures For Prostate Cancer Validated
Chukwuma Maunya 9 hours ago Features
Several studies have shown that more Nigerian men are dying due to complications of prostate cancer and prostate enlargement. But researchers have scientifically validated more natural products including the seeds of pawpaw and watermelon that could be successfully used to prevent and treat prostate problems without unpleasant side effects. CHUKWUMA MUANYA writes.
The prostate cancer is the malignant tumour of the prostate gland of male reproductive organ, which may be life threatening, when spread to other body parts, predominantly towards lymph nodes, and bones.
Prostate enlargement, also called Benign Prostatic Hyperplasia is a noncancerous increase in size of the prostate. Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control. Complications can include urinary tract infections, bladder stones, and chronic kidney problems.
According to a report published by Cancer Research, UK, an estimated 14 million cases of cancer reported worldwide and nearly half-8.2 million people died from cancer. The cases of cancer is expected to increase to 24 million by 2035, therefore, the death toll from cancer is expected to increase in the future.
Many studies have shown that the major factor contributing in prostate cancer is the age, because men who have the prostate cancer are between 65 and 80 years, and it is rare in men who are under than 40 years.
Hormone Therapy For Prostate Cancer
Hormone therapy is usually done to slow the growth or reduce the size of your prostate tumour. The male hormone testosterone is useful for the normal development of the prostate by binding to androgen receptors, AR. These ARs play a key role in stimulating prostate cancer cells to grow. Therefore, in hormone therapy, our goal is to reduce the production of testosterone and/or block its binding to ARs and cancer cells.
We may recommend hormone therapy:
- if you have advanced disease
- along with radiation therapy for high risk individuals to get better results
- if your cancer has returned after treatment or has spread to other tissues
Our oncologists may recommend drugs such as Goserelin , Bicalutamide and Abiraterone depending on the type of hormone therapy best suited to you.
Surgery to remove the testicles also known as orchiectomy is another form of hormone therapy. Since most of the testosterone produced by the body is done by the testicles, this procedure greatly reduces the amount of testosterone in the body and helps slow growth of prostate cancer cells.
Side effects of hormone therapy include reduced sex drive, weight gain, erectile dysfunction and hot flashes
Read Also: Can You Reduce An Enlarged Prostate
Symptoms Of An Enlarged Prostate
When tissues in the prostate enlarge, they may apply pressure to the urethra and partially block urine flow. This may trigger the following symptoms:
- Difficulty starting urination
- Dribbling at the end of urination
- Incomplete emptying of the bladder
Less than half of men with BPH show symptoms.
Medicine For Prostate Enlargement In Ghana
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Take A Look At What Prostara Will Do For You
Any man who is constantly struggling with the symptoms of prostate enlargement understands just how much of an effect these issues can have on overall quality of life. Thanks to Prostara, men of practically any age can find powerful and natural relief from urinary symptoms while taking positive measures to protect their prostate health.*
Prostara is a proprietary formula made with scientifically researched ingredients that:
- Provides relief from numerous symptoms of prostate enlargement, including urgency and weak stream*
- Protects against cellular damage with powerful antioxidants that destroy free radicals*
- Optimizes zinc levels in important prostate tissues to support ideal structure and function*
- Inhibits the production of compounds thought to play a role in unwanted bladder issues*
- Exerts anti-estrogenic effects inside the body to curb excessive estrogen production, which can contribute to undesirable symptoms *
Cystoscopy & Diagnostic Ureteroscopy
A Cystoscopy is a diagnostic test that assesses the health of your urethra and bladder. A small scope is inserted in your urethra to examine your urethra and collect any tissue samples for further testing and examination. Similarly, a diagnostic Ureteroscopy is an examination that assesses the health of your kidneys and ureter.
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Herbal Medicine For Gonorrhea In Ghana
Aloe Vera for Gonorrhea
Aloe Vera is a herbal medicine with numerous benefits. Nevertheless, the plant comes with one species known as Barbadensis Milla that can help in the cure for Gonorrhea. For the reason that this ailment is resilient to numerous types of medication, herbal medicines such as aloe vera are mostly recommended as complementary or substitute alternatives. The aloe vera plant has displayed outstanding realization in eradicating the contagious infections and depressing soreness. A mixture of honey and aloe vera will offer you the required defense and relieve from the infection of Gonorrhea. Additionally, as per numerous studies, honey has been recognized as one of the best remedy for many bacteria that are resistant to drugs.
Clinical Studies On Use Of Croton Membranaceus
Only one observational clinical study on the use of C. membranaceus on clinical BPH has been published to date. In a study of 33 patients presenting with lower urinary symptoms due to BPH, but with 30 of them completing the study, Asare et al showed that a freeze-dried C. membranaceus ethanol root extract administered orally at a dose of 20mg eight hourly for 3 months led to an improvement in the international prostate symptoms score with a shift from severe lower urinary symptoms to moderate to mild symptoms.
The tools used in this observational study were the International prostate symptoms score , International index of erectile function and abdomino-pelvic ultrasound to determine prostate size and post void residual urine volume. The proportion of patients with severe symptoms reduced from 37% to 0% while the proportion with mild symptoms increased from 23% to 43%. Those with moderate symptoms however increased from 40% to 57%.
Thus, although there was improvement in those with severe symptoms there still remained a significant number of them with moderate symptoms which raises issue about the effectiveness of the C. membranaceus extract. Reduction in prostate size was also observed in the study, with the mean prostate volume decreasing from 101.8 to 54.5grams. This reduction in the glandular weight reflects a reduction in possible glandular components.
Also Check: How To Get Your Prostate Checked
History Of Traditional Herbal Medicine In Ghana
Herbal treatment is a primordial medicinal approach that offers Ghanas populace with secure, efficient and inexpensive cure since time memorial. Even as we speak, the current generation in most of the African countries relies heavily on herbal medicine for various health cure requirements such as medicines for sexually transmitted infections. In Ghana, almost 75% of the population is recorded to use traditional cure at certain phases in their lifetime. According to recent findings, the majority of physicians proficient in Ghana have undertaken herbal medicine course as part of the training.
Internationally, there is a general acknowledgment that the treatment that was defined as primeval would be mans saving element. Therefore, in a span of twenty years, the opinions of herbs being considered witchcraft has switched a major medicine component in treating diseases in the contemporary World.
Determinations to support the use of use of herbal medicine in Ghana began with the establishment of the Ghana Psychic and Traditional Healers Association in 1961 with the then president Dr. Kwame Nkrumah. The objective of the organization was to uphold, promote and protect the best in mental and natural treatment in Ghana. After a couple of years, with the help from the global organization known as United States Agency for International Development Danfa Health Centre was established and this aimed at training traditional birth attendants.
Survey Of Prostate Cancer In Accra Ghana
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|First Posted : June 21, 2006Last Update Posted : May 20, 2020|
- Study Details
This study, conducted at Korle-Bu Hospital in Accra, Ghana, will help elucidate the roles of lifestyle and genetic factors in prostate cancer risk. There is a strong variation in risk of prostate cancer throughout the world. The rates of the disease among African Americans are some of the world s highest. In the United States, the incidence of prostate cancer is 70 percent higher in African Americans than in white Americans and the death rate in African Americans is almost double that of white Americans. The reasons for this excessive risk are unknown, but both genetic and lifestyle factors have been suggested.
Because Africans and African Americans share similar genetic ancestry but have vastly different lifestyles, a better understanding of the rates and risk factor profiles for prostate cancer among Africans will provide important clues to what causes the disease. This study will try to assess the incidence of prostate cancer in the West African nation of Ghana. The study has two components:
Also Check: How Do Prostate Cancer Patients Die
Treatment Options For Enlarged Prostate
For men over 50, prostate problems are common. The prostate gland is located just below the bladder and surrounds the top portion of the urethra, which is the tube that drains urine from the bladder. The prostate’s primary function is to produce the fluid that nourishes and transports sperm.
As men age, the prostate gland tends to grow larger. Benign prostatic hyperplasia, also called prostate gland enlargement, can cause uncomfortable urinary symptoms, such as blocking the flow of urine out of the bladder, or bladder, urinary tract or kidney problems. Fortunately, a wide variety of treatments are available for enlarged prostate, including medication, minimally invasive therapies and surgery.
On the next Mayo Clinic Radio program, Dr. Mitchell Humphreys, a Mayo Clinic urologist, will highlight prostate health and treatment options for benign prostatic hyperplasia. Also on the program, Dr. Francisco Lopez-Jimenez, a Mayo Clinic cardiologist, will discuss sex after a heart attack. And Dr. Bruce Levy, a Mayo Clinic orthopedic surgeon, will share how his patients’ experiences with lack of privacy during surgery led him and his wife to found a new company, COVR Medical.
To hear the program, find an affiliate in your area.
Use the hashtag #MayoClinicRadio, and tweet your questions.
Mayo Clinic Radio is on iHeartRadio.
Access archived shows or to the podcast.
Mayo Clinic Radio produces a weekly one-hour radio program highlighting health and medical information from Mayo Clinic.