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Cutting Edge Prostate Cancer Treatment

Ashesh B Jani Md Msee Fastro

Anthony Bamgbose – Driven for a Second Opinion and Innovative Prostate Cancer Care
  • Radiation Oncologist
  • Dr. Jani specializes in the treatment of genitourinary malignancies including cancer of the prostate, bladder, kidney, testes and urethra.
  • Professor, Department of Radiation Oncology, Emory University School of Medicine
  • Rev. Jones provides spiritual and emotional support for oncology patients and their caregivers at Emory University Hospital Midtown.
  • Chaplain and Spiritual Health Fellow, Emory University Hospital Midtown

Treatment Option Overview For Prostate Cancer

Local treatment modalities are associated with prolonged disease-free survival for many patients with localized prostate cancer but are rarely curative in patients with locally extensive tumors. Because of clinical understaging using current diagnostic techniques, even when the cancer appears clinically localized to the prostate gland, some patients develop disseminated tumors after local therapy with surgery or radiation.

Treatment options for each stage of prostate cancer are presented in .

A New Type Of Pet Scan

One breakthrough is the approval of a new technology to detect advanced prostate cancers: prostate-specific membrane antigen PET scanning. It works by using radioactive tracers that attach to a protein called PSMA often found on prostate cancer cells, per the American Cancer Society. PSMA PET scanning has the potential to significantly change how we treat men with high-risk, clinically localized prostate cancer as well as recurrent prostate cancer, says Sam Haywood, M.D., urologist at the Glickman Urological and Kidney Institute at Cleveland Clinic in Ohio. By more sensitively detecting prostate cancer metastasis, this allows for the appropriate staging and treatment.

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Personalized Prostate Cancer Care With Genetic Testing

Much like the prostate specific antigen that is used inPSA testing, there are other biomarkers that may help your physician diagnose prostate cancer. HALO Dx works with ExosomeDx and is proud to offer the ExoDx Prostate Test, a urine-based test that is used similarly to a PSA test before biopsy. The test analyzes three cancer-specific biomarkers found in the urine that are associated with aggressive prostate cancer. These biomarkers or genes in this case are: ERG, PCA and SPDEF. This simple non-invasive test can help assess your risk of having clinically significant high-grade prostate cancer and help you and your doctor determine whether to proceed with or defer a prostate biopsy.

Along with traditional pathology of the biopsy results, HALO Dx offers genomic tests on the same tissue sample to help identify the appropriate treatment option and help determine the metastatic potential of the tumor through the . We have seen impressive results over the years and have demonstrated that the Decipher test can be used to help predict response to Laser Focal Therapy.

Moffitt Cancer Center On Cutting Edge Of New Treatment That Could Save Lives Of Advanced Melanoma Patients

The Cutting Edge In Indian Medicine

Brand new therapy for advanced melanoma patients

Briona Arradondo reports

TAMPA, Fla. – Moffitt Cancer Center is on the cutting edge of treatment for advanced melanoma, and now they’re using cancer to fight cancer.

A new type of immunotherapy is expected to save the lives of patients with the disease when no other treatments work.

READ:Experimental cancer vaccine shows promising results in animal studies, NIH researchers find

“The standard treatment for melanoma involves either IV infusions of immunotherapy or we also have the ability to target the mutations of the tumor with a combination of pills that’s targeted inhibitor therapy. So probably about half of patients will have long term benefits from those types of treatments,” said Amod Sarnaik, a surgical oncologist at Moffitt Cancer Center in Tampa. “But that leaves another half of patients where the treatment doesn’t quite work the way we want it to. Those patients would have had to go on to chemotherapy, which we all know for at least for melanoma doesn’t last quite long and has a lot of side effects.”

Sarnaik helped lead research on a new kind of treatment called adoptive cellular therapy with tumor infiltrating lymphocytes. He said Moffitt first started looking into cellular therapy in 2008, and the treatment was created by the National Cancer Institute.

Whats new is how the therapy is being used as an option to treat advanced melanoma patients.

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What Each Team Member Does

Your radiation oncologist is your physician and will meet with you once a week to review your progress and discuss any questions or concerns you may have. The radiation oncologists who provide clinical care at at our proton therapy facility are all members of the University of Washington Physician Group and hold faculty positions within the UW School of Medicine.

Your care team nurse will provide day-to-day care and help coordinate any additional medical services you might need during your proton treatment, including: arranging for blood tests, scans, medical appointments or other services you need. Your clinical nurse is experienced in radiation therapy.

Your radiation therapist will confirm that you are positioned correctly. This will ensure your treatment is delivered precisely according to your physicianâs treatment plan. They will deliver your daily treatment and will remain close by while you receive therapy.

Patient care coordinators manage the exchange of your medical records, collect information for evaluating your individual care plan and schedule your initial consultation. They also assist you in understanding your insurance, Medicare or Medicaid coverage, and help coordinate your payment and manage your costs.

A medical physicist monitors the equipment and procedures used in therapy. They run patient-specific checks on your treatment plan to be sure you receive the correct dose of protons targeted precisely to your tumor.

Treatment Options Under Clinical Evaluation For Stage Ii Prostate Cancer

Treatment options under clinical evaluation for patients with include the following:

Ultrasound-guided percutaneous cryosurgery

Cryosurgery is a surgical technique that involves destruction of prostatecancer cells by intermittent freezing of the prostate with cryoprobes followed by thawing. Cryosurgery is less wellestablished than standard prostatectomy, and long-term outcomes are not as well established as with prostatectomy or radiation therapy. Serious toxic effects include:

  • Bladder outlet injury.
  • Sexual impotence.

The frequency of other side effects and the probability of cancer control at 5 years’ follow-up have varied among reporting centers, and series are small compared with surgery and radiation therapy.

High-intensity focused ultrasound

High-intensity focused ultrasound has been reported in case series to produce good local disease control. However, it has not been directly compared with more standard therapies, and experience with it is more limited.

Proton-beam radiation therapy

There is growing interest in the use of proton-beam radiation therapy for the treatment of prostate cancer. Although the dose distribution of this form of charged-particle radiation has the potential to improve the therapeutic ratio of prostate radiation, allowing for an increase in dose to the tumor without a substantial increase in side effects, no randomized controlled trials have been reported that compare its efficacy and toxicity with those of other forms of radiation therapy.

Recommended Reading: Prostate And Bladder Cancer Survival Rate

Kent Police Officer Takes Charge Of His Toughest Case Yet

Winding through the rainy streets of the City of Kent, muffled voices over the radio in the background, police officer Garth Corner was on a routine call from the dispatcher when he realized the vision in his left eye was blurrier than normal.

It was time for him to get glassesor so he thought.

Garth experienced a slow deterioration in his vision but chalked it up to aging. He put off seeing his primary physician or an optometrist he was too busy with his family, hobbies, and job serving the community.

After more than one year of blurred vision, Garth visited his doctor where he learned that his eye condition might require more than glasses. He was referred to ocular oncologist Andrew Stacey, M.D. and diagnosed with ocular melanoma.

As a healthy, active person with no family history of cancer, Garth was in shock. He never thought he would get cancer or that it was possible to get melanoma in one’s eye.

Faced with the risk of losing his eyesight, Garth worried that his job which relies on vision and awareness would be impossible to perform and therefore disrupt his ability to provide for his wife and two daughters. Never in his 10 years on the Kent police force or his 21 years in the military had he encountered a more frightening obstacle.

With his doctors guidance, Garth decided on proton therapy because it was less impactful on his daily life. By the end of the consultation, Garth had a plan of action that allowed him to take charge of his treatment.

Duke Cancer Center Offers New Treatment For Metastatic Prostate Cancer

YLYH: Cutting-Edge Cancer Care

Terence Wong, MD, PhD, and Stacy Wood, a Duke Health nuclear medicine technologist, provides treatment to a patient.

Men with advanced metastatic prostate cancer that has not responded to other treatments may now benefit from a new radiopharmaceutical treatment called PLUVICTOTM . Duke is one of the first cancer centers in the Southeastern region to offer PLUVICTOTM following its FDA approval in March 2022. Studies show it can extend the lives of people with this aggressive form of prostate cancer, even in the late stages, said Terence Wong MD, PhD, a nuclear radiologist at Duke Health.

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Cutting Edge Prostate Cancer Treatment

If you are diagnosed with prostate cancer, Gibbs Cancer Center & Research Institute at Pelham can help you through treatment comfortably and conveniently with cutting edge technology.

Prostate cancer is second only to skin cancer as the most common cancer diagnosis in men. With CyberKnife at Gibbs Cancer Center & Research Institute at Pelham, located in Greer, radiation therapy for prostate cancer is completed in just five sessions. Compare that number with the 40 to 45 sessions using conventional radiation therapy.

CyberKnife’s robotic tracking technology enables continuous coordination with tumor movement during treatment. This is especially important if when receiving treatment for prostate cancer. CyberKnife candidates include most low-risk and favorable intermediate-risk prostate cancer patients. Prostate size is not an issue.

Treatment at Gibbs Cancer Center & Research Institute at Pelham gives you access to the latest advancement in CyberKnife technology with the recent introduction of a second generation multi-leaf colmnater. A state-of-the-art upgrade that, when combined with the CyberKnife’s advanced robotic targeting, has cut prostate cancer treatment times in half, while reducing radiation to other vital organs.

Effectiveness of CyberKnife therapy for prostate cancer has proven to be similar to other treatment outcomes at five years.

The Sperling Prostate Center Advantage

Our philosophy is to match the treatment with the disease. Our BlueLaser 3T mpMRI-Guided Biopsy is the most responsible and accurate way to know your disease before making a treatment decision. We help patients avoid the risk of under-treating aggressive disease, or over-treating insignificant disease that can safely be monitored. We pride ourselves on having attained international recognition for excellence in real-time MRI-guided prostate cancer diagnosis.

If BlueLaser 3T mpMRI detects cancer, a biopsy is essential because prostate cancer may not show early symptoms, though certain warning signs indicate increased prostate cancer risk:

  • An elevated or rising PSA blood test result
  • An abnormal digital rectal exam
  • A family history of prostate cancer or breast cancer
  • Being of African-American descent
  • Exposure to certain cancer-causing toxins, e.g. Vietnam vets exposed to Agent Orange
  • In later stages, prostate cancer may show symptoms such as urinary difficulties, blood in urine, pelvic or back pain, and bone pain. See a doctor if any of these symptoms occur.

Recommended Reading: What To Expect With Prostate Cancer

Leading Specialists In Laser Ablation Procedure For Prostate Tumors

Are you, or is someone you love, at risk for prostate cancer? Have you been told that your PSA test results are high and you need a biopsy? Have you had a positive biopsy? Are you exploring alternatives to surgery or radiation?

The world of prostate cancer can be overwhelming, with confusing and conflicting information about the disease and its treatments, but little explaining what is happening inside your own body.

Rest assured. The Sperling Prostate Center team is here to put your mind at ease.

Patient Greyson Quarles tells his story

The Sperling Prostate Center in Florida offers noninvasive advanced imaging as a revolutionary first step in prostate tumor detection and diagnosis. The more you know about what is happening in your body, the more informed and rational your healthcare decisions will be. The best education is having a clear picture of what is going on within your own body. Dr. Sperling and his team will welcome and support you as advanced images are captured, your prostate gland is mapped, and the results are explained to you in a way you can fully understand.

Our Approach To Prostate Cancer

Robotic cancer surgery

Prostate cancer is the most common type of cancer in American men. 1 in 8 men will develop it during their lifetimes. Owing to advances in early diagnosis and effective treatments, the majority of men with prostate cancer will not die from it.

Most men begin to suspect they have prostate cancer after obtaining an elevated PSA level or abnormal digital rectal examination. The PSA blood test measures the level of prostate-specific antigen in the blood.

The challenge for physicians is determining which patients with high PSA levels need invasive tests such as biopsies, and which patients diagnosed with prostate cancer need localized treatment to the prostate and surrounding tissues, such as surgery or radiation.

The Siteman Cancer Center is the only National Cancer Institute-designated Comprehensive Cancer Center in Missouri and is ranked among the top cancer facilities in the nation by U.S. News & World Report.

Read more about our mission, vision and history.

At Siteman, we diagnose and treat prostate cancer with the most sophisticated imaging techniques, diagnostics, and therapies available. Our multidisciplinary team sees approximately 1,000 new prostate cancer patients a year. Each patient receives an individualized treatment plan for his prostate cancer.

Hear from patients whove been treated for prostate cancer at Siteman.

Recommended Reading: Prevalence Of Prostate Cancer By Age

New Developments In Cancer Research

Progress in the field.In recent years, advancements in research have changed the way cancer is treated. Here are some recent updates:

Uterine cancer.Women who use chemical hair straighteners frequently could have a higher risk of developing uterine cancer than women who have never used the products, according to new findings from a national study that has followed nearly 34,000 U.S. women for more than a decade.

Breast cancer.A new study suggests surgery may not always be necessary for all breast cancer patients. A small early-stage clinical trial found that a carefully selected group of patients who responded remarkably well to chemotherapy could skip surgery altogether.

Cancer vaccines.For a long time, the promise of cancer vaccines that would protect healthy people at high risk of cancer has only dangled in front of researchers. Now, though, encouraging animal data and preliminary studies in human patients are making some doctors feel optimistic.

Rectal cancer.A small trial that saw 18 rectal cancer patients taking the same drug, dostarlimab, appears to have produced an astonishing result: The cancer vanished in every single participant. Experts believe that this study is the first in history to have achieved such results.

Youre not just destroying the cancer cells youre smart-bombing the place that the tumor has found for itself to live.

Treating Prostate Cancer That Has Spread To The Bones

Doctors are studying the use of radiofrequency ablation to help control pain in men whose prostate cancer has spread to one or more areas in the bones. During RFA, the doctor uses a CT scan or ultrasound to guide a small metal probe into the area of the tumor. A high-frequency current is passed through the probe to heat and destroy the tumor. RFA has been used for many years to treat tumors in other organs such as the liver, but its use in treating bone pain is still fairly new. Still, early results are promising.

Also Check: What Are Side Effects Of Radiation Treatment For Prostate Cancer

Valerie Buckley Ms Cso Rd Ld

  • Nutrition Advisor
  • A Registered Dietitian, Ms. Buckley provides cancer patients who are undergoing treatment at Winship Cancer Institute with personalized nutrition advice.
  • Clinical Dietitian, Winship Cancer Institute of Emory University
  • Ms. Burke works with oncology patients treated at Emory Decatur Hospital and Emory Hillandale Hospital
  • Social Worker, Oncology, Emory Decatur Hospital
  • Ms. Cahn provides comprehensive genetic counseling services for individuals who are at risk for hereditary cancer.
  • Licensed Certified Genetic Counselor, Winship Cancer Institute of Emory University

Content Provided By Spartanburg Regional Healthcare System

How High Intensity Focused Ultrasound Treatment Works for Prostate Cancer Works
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Content provided by Spartanburg Regional Healthcare System

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If you are diagnosed with a prostate cancer diagnosis, Gibbs Cancer Center & Research Institute at Pelham can help you through treatment comfortably and conveniently with cutting edge technology.

Prostate cancer is second only to skin cancer as the most common cancer diagnosis in men. With CyberKnife at Gibbs Cancer Center & Research Institute at Pelham, located in Greer, radiation therapy for prostate cancer is completed in just five sessions. Compare that number with the 40 to 45 sessions using conventional radiation therapy.

CyberKnifes robotic tracking technology enables continuous coordination with tumor movement during treatment. This is especially important if when receiving treatment for prostate cancer. CyberKnife candidates include most low-risk and favorable intermediate-risk prostate cancer patients. Prostate size is not an issue.

Treatment at Gibbs Cancer Center & Research Institute at Pelham gives you access to the latest advancement in CyberKnife technology with the recent introduction of a second generation multi-leaf colmnater. A state-of-the-art upgrade that, when combined with the CyberKnifes advanced robotic targeting, has cut prostate cancer treatment times in half, while reducing radiation to other vital organs.

Effectiveness of CyberKnife therapy for prostate cancer has proven to be similar to other treatment outcomes at five years.

What to Expect

Recommended Reading: Prostate Cancer Return After Prostatectomy

Biggest Breakthroughs In Advanced Prostate Cancer Treatment

by Health Writer

Prostate cancer is most often diagnosed at an early and highly treatable stagebut if youre one of the men with advanced-stage prostate cancer at diagnosis, youre in a club whose numbers have risen in the last decade, according to the Centers for Disease Control and Prevention . Thankfully, advancements in prostate cancer research have led to promising improvements in treatment possibilities for this club. We spoke to the experts to learn more about breakthroughs that are changing the treatment game in prostate cancer.

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