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Prostate Cancer Spread To Colon

Where Does Colon Cancer Spread

How Cancer Spreads (Metastasis) – Michael Henry, PhD

When you are diagnosed with colon cancer it means that you had abnormal cells invade your colon. The abnormal cells grow into colon polyps. Not all colon polyps are cancerous. Sometimes the polyps turn cancerous and can spread to surrounding tissues.

Colon cancer symptoms are often mild and can be missed early on in the disease. This means you may not notice any symptoms until the disease has progressed into advanced stages and spread beyond the colon. This is why it is important to get screened for colon cancer at each yearly physical after the age of 50. Once the disease has spread it may be harder to treat.

Where Does Prostate Cancer Spread

The most common place for prostate cancer to spread to is the bones. It can also spread to the lymph nodes, liver and lungs and other organs.

A large tumour in the prostate gland can spread into or press on areas around the prostate, such as the back passage or urethra. The urethra is the tube which carries urine from the bladder to the outside of the body.

What Is The Relationship Between Colon Cancer And Prostate Cancer

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Bladder And Urinary Troubles

A prostate tumor that has grown significantly in size may start to press on your bladder and urethra. The urethra is the passage the carries urine from your bladder out of your body. If the tumor is pressing on your urethra, you might have trouble passing urine.

One of the common areas for prostate cancer to spread to is the bladder, because the two organs are close. This can cause additional problems with urination and bladder function.

Some symptoms your bladder and urethra are being affected by cancer include:

  • urinating more frequently
  • getting up in the middle of the night to pee
  • having blood in your urine or semen
  • feeling like you have to urinate often and not actually passing anything

Its not as common, but prostate cancer can also spread to your bowel. The cancer first spreads to the rectum, which is the part of your bowel closest to the prostate gland.

Symptoms of cancer thats spread to the bowels include:

  • stomach pain

How Long Is A Course Of Chemotherapy

Colon Cancer Treatment (PDQ®)âHealth Professional Version ...

In the majority of cases for best results the patient will need regular chemotherapy over a specific period. A protocol plan is drawn up which specifies when treatment sessions will occur and for how long.

A course of chemotherapy may be just a one-day treatment, or can last for a few weeks it will depend on the type and stage of the cancer . If the patient requires more than one course of treatment there will be a rest period for his/her body to recover. This could be a one-day treatment followed by a weeks rest period, followed by another one-day treatment followed by a three-week rest period, etc. This may be repeated many times.

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What Gets Stored In A Cookie

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In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a website to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it.

Stem Cell Or Bone Marrow Transplant

A stem cell transplant, sometimes called bone marrow transplant, replaces damaged blood-forming cells with healthy ones. The procedure takes place following large-dose chemotherapy or radiation therapy to kill cancer cells and to stop your stem cells from producing cancerous cells.

Stem cell transplants can be used for several types of cancer, including multiple myeloma and some kinds of leukemia.

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Symptoms Of Metastatic Cancer

Metastatic cancer may or may not cause symptoms, and the potential symptoms may vary depending on the type of cancer and where its spread.

In general, however, there are certain symptoms that tend to come with metastatic cancer, including:

  • Fatigue
  • Pain
  • Difficulty breathing

There may also be symptoms specific to the site where the cancer has spread. For example:

  • Cancer that has spread to a bone may cause pain and an increased risk of fractures.
  • Cancer that has spread to the brain may cause headaches, seizures or dizziness.
  • Cancer that has spread to a lung may cause difficulty breathing or shortness of breath.
  • Cancer that has spread to the liver may cause jaundice and abdominal swelling.

Metastatic Spinal Cord Compression

Where Does Prostate Cancer Spread To?

Metastatic spinal cord compression happens when cancer cells grow in or near to the spine and press on the spinal cord. MSCC isnt common, but you need to be aware of the risk if your prostate cancer has spread to your bones or has a high risk of spreading to your bones. The risk of MSCC is highest if the cancer has already spread to the spine. Speak to your doctor or nurse for more information about your risk.

MSCC can cause any of the following symptoms.

  • Pain or soreness in your lower, middle or upper back or neck. The pain may be severe or get worse over time. It might get worse when you cough, sneeze, lift or strain, or go to the toilet. It might get worse when you are lying down. It may wake you at night or stop you from sleeping.
  • A narrow band of pain around your abdomen or chest that can move towards your lower back, buttocks or legs.
  • Pain that moves down your arms or legs.
  • Weakness in your arms or legs, or difficulty standing or walking. You might feel unsteady on your feet or feel as if your legs are giving way. Some people say they feel clumsy.
  • Numbness or tingling in your legs, arms, fingers, toes, buttocks, stomach area or chest, that doesnt go away.
  • Problems controlling your bladder or bowel. You might not be able to empty your bladder or bowel, or you might have no control over emptying them.

Dont wait

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How To Tell If Your Cancer Has Metastasized

Prostate cancer metastasis may be suspected if you have specific symptoms such as new lower back pain or elevated liver enzymes. These may be signs your cancer has spread to your spine or your liver, respectively. If your prostate-specific antigen levels continue to rise despite treatment, especially if they are rising particularly fast, this may be a sign that cancer is metastasizing somewhere in your body.

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The Top 7 Signs Of Advanced Prostate Cancer

In the early stages, you may not notice any symptoms related to prostate cancer. This is why screenings are important. Symptoms can sometimes be noticed for the first time when the cancer advances.

Advanced prostate cancer, also called metastatic cancer, means the cancer has spread to other areas of your body beyond your prostate gland. The most common areas for prostate cancer to spread are your bladder, rectum, and bones. It can also spread to your lymph nodes, liver, lungs, and other body tissues.

Whether youve just been diagnosed or youre in treatment, its also important to know the signs of advanced cancer. Cancer can behave differently depending on your genetics, so not every person will experience the same symptoms in the same way.

Read on to learn more about the seven top symptoms of advanced prostate cancer and how to spot them.

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What Is My Outlook

If youre diagnosed with advanced prostate cancer, you may want to know how well your treatment is likely to control your cancer and for how long it will control it. This is sometimes called your outlook or prognosis. But not all men will want to know this.

While it isnt possible to cure advanced prostate cancer, treatments can help keep it under control, often for several years. Treatments will also help manage any symptoms, such as pain.

No one can tell you exactly what your outlook will be, as it will depend on many things such as where the cancer has spread to, how quickly it has spread, and how well you respond to treatment. Some men may not respond well to one treatment, but may respond better to another. And when your first treatment stops working, there are other treatments available to help keep the cancer under control for longer. Speak to your doctor about your own situation and any questions or concerns you have.

What About Other Treatments That I Hear About

Prostate Cancer: Signs, Symptoms, and Complications

When you have cancer you might hear about other ways to treat the cancer or treat your symptoms. These may not always be standard medical treatments. These treatments may include vitamins, herbs, diets, and other things. You may wonder if these treatments are safe and whether they could help you.

Some of these treatments are known to help, but many have not been tested. Some have been shown not to help. A few have even been found to be harmful. Talk to your doctor about anything youre thinking about using, whether its a vitamin, a diet, or anything else.

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Treatments To Help If It Spreads

If colon cancer spreads, you and your doctor will come up with an aggressive treatment plan to try and stop cancer from spreading. The treatments go by Stage and include:

Stage 1 and 2 Treatments

If the cancer is still confined to just the colon, surgical intervention can usually prevent the spread of colon cancer.

Stage 3 Treatments

If the cancer begins to spread to the lymph nodes, any lymph nodes near the start of the cancer will be removed. If the cancer is found in distant lymph nodes near the liver or lungs, they will also be removed.

Stage 4 Treatments

Once colon cancer has invaded the liver, lungs, bones, and/or brain, the treatment plan will be to give both chemotherapy and radiation in cycles to kill off cancer cells. Radiation may also be given early in Stage 1 or 2 to prevent the spread.

What About Other Treatments I Hear About

When you have cancer you might hear about other ways to treat the cancer or treat your symptoms. These may not always be standard medical treatments. These treatments may be vitamins, herbs, special diets, and other things. You may wonder about these treatments.

Some of these are known to help, but many have not been tested. Some have been shown not to help. A few have even been found to be harmful. Talk to your doctor about anything youre thinking about using, whether its a vitamin, a diet, or anything else.

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Some Colorectal Tumors Are Born To Be Bad

To get a better handle on the timing of metastasis, the team developed a computer model to simulate the evolution of millions of virtual tumors under different conditions.

We could then compare the simulated data with the observed patient data using various statistical techniques, Dr. Curtis explained.

The modeling data indicated that metastasis begins very early during tumor developmentwhen the primary tumor is smaller than the tip of a sharpened pencil.

In other words, Dr. Curtis said, some tumors may be “born to be bad.

The team next investigated whether the results from their small set of paired samples of primary and metastatic tumors from patients could be extended to a larger number of patients.

They analyzed publicly available data from 938 people with metastatic colorectal cancer and 1,813 people with early-stage, nonmetastatic colorectal cancer whose medical histories were known. The primary tumors of these patients had been profiled to identify genetic changes in known cancer-associated genes.

This analysis showed that certain genetic changes tend to occur together, and that specific combinations of three to five mutations were more common in patients with metastatic cancer than in those with nonmetastatic disease, suggesting that specific combinations of early genetic changes confer the potential for tumor cells to spread.

If confirmed in future studies, this information could potentially be used to guide treatment decisions, she said.

Stage 3 Pericardial And Testicular Mesothelioma

Prostate Cancer Treatment (03): Patterns of Spread

Doctors and researchers do not clearly define stage 3 pericardial or testicular mesothelioma due to their rare nature.

Only 1% to 2% of mesothelioma cases are pericardial, which means cancer forms within the sac that protects the heart. Therefore, a diagnosis for this disease is unlikely until the late stages, after metastasis to the lungs or chest cavity.

Doctors evaluate testicular mesothelioma tumor characteristics by using staging guidelines for general testicular cancer. For example, doctors more commonly refer to stage 3 testicular mesothelioma as late-stage cancer. This description indicates that cancer has spread beyond the lining of the testicles to other tissues such as lymph nodes or bone.

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What Is Colon Or Rectal Cancer

Cancer that starts in the colon or rectum is often called colorectal cancer. It might also be called colon cancer or rectal cancer. It starts when cells in the colon or rectum grow out of control and crowd out normal cells.

Cancer cells can spread to other parts of the body. Cancer cells from the colon or rectum can sometimes travel to the liver and grow there. When cancer cells do this, its called metastasis. The cancer cells in the new place look just like the ones that started growing in the colon or rectum.

Cancer is always named for the place where it starts. So when colorectal cancer spreads to the liver , its still called colorectal cancer. Its not called liver cancer unless it starts from cells in the liver.

Ask your doctor to show you on this picture where your cancer is found.

Soreness In The Groin

When prostate cancer spreads, its common for cancer cells to go to your lymph nodes and then move to more areas of your body. The lymph nodes are a network of glands that help your body filter fluids and fight infections.

There are several lymph nodes in your groin. These are the ones closest to your prostate, so its common for the cancer to spread to them first. Cancer cells prevent your lymph nodes from draining fluid and working properly. When this happens, your lymph nodes swell. As a result, you might experience pain or soreness in the area.

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What Will Happen After Treatment

Youll be glad when treatment is over. But its hard not to worry about cancer coming back. When cancer comes back it is called a recurrence. Even when cancer never comes back, people still worry about it. For years after treatment ends, you will see your cancer doctor. At first, your visits may be every few months. Then, the longer youre cancer-free, the less often the visits are needed.

Be sure to go to all follow-up visits. Your doctors will ask about your symptoms, examine you, and might order blood tests and maybe other tests to see if the cancer has come back.

Having cancer and dealing with treatment can be hard, but it can also be a time to look at your life in new ways. You might be thinking about how to improve your health. Call us at 1-800-227-2345 or talk to your doctor to find out what you can do to feel better.

You cant change the fact that you have cancer. What you can change is how you live the rest of your life, making healthy choices and feeling as good as you can.

Drugs To Treat Cancer Spread To Bone

Prostate Cancer Spread Metastatic To Bones Life Expectancy ...

If prostate cancer spreads to other parts of the body, it almost always goes to the bones first. These areas of cancer spread can cause pain and weak bones that might break. Medicines that can help strengthen the bones and lower the chance of fracture are bisphosphonates and denosumab. Sometimes, radiation, radiopharmaceuticals, or pain medicines are given for pain control.

Side effects of bone medicines

A serious side effect of bisphosphonates and denosumab is damage to the jaw, also called osteonecrosis of the jaw . Most people will need to get approval from their dentist before starting one of these drugs.

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Pearls And Other Issues

PSA Testing: The Pros and the Cons

Prostate Specific Antigen is a protein produced by the prostate and is abundant in semen. Its natural function is to divide seminogelin in the semen, which helps in liquefaction. The expression of PSA is androgen-regulated.

It was originally used as a prostatic tissue stain to help determine the etiology of tumors of unknown origin. Later, serum levels of PSA were used as a prostate cancer screening tool because serum PSA levels start to increase significantly about seven to nine years before the clinical diagnosis of malignancy. While a good indicator of prostatic disorders, PSA elevation is not specific for cancer as it is also elevated in benign prostatic hyperplasia, infection, infarction, inflammation and after prostatic manipulation. It also cannot reliably distinguish between low risk/low grade disease and high risk/high grade cancers.

About 80% of the patients currently diagnosed with prostate cancer are initially investigated due to an elevated serum PSA.

While it unquestionably increases prostate cancer detection rates, the value of PSA testing is less clear in avoiding overtreatment, improving quality of life and lengthening overall survival which is why routine PSA screening for prostate cancer remains quite controversial.

PSA testing became widely available in the United States in 1992, and since then, prostate cancer detection rates have increased substantially.

The Current USPSTF Recommendation

Against PSA Screenings

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